Epstein-Barr Virus

The SERION ELISA classic Epstein-Barr Virus EA IgG, VCA IgG, IgM and EBNA1 IgG tests are quantitative and qualitative immunoassays for the detection of human antibodies in serum or plasma directed against components of the Epstein-Barr Virus (EBV). The SERION ELISA classic Epstein-Barr Virus EA IgG and SERION ELISA classic EBV VCA IgM are recommended for the detection of acute infections or reactivations. The SERION ELISA classic Epstein-Barr Virus VCA IgG determines primary and recent infections. The SERION ELISA classic EBNA1 IgG is recommended for the determination of past infections. The SERION ELISA classic EBV VCA and EBNA1 IgG tests are validated for the demonstration of intrathecally synthesized antibodies in CSF diagnostics.

Highlights

• Combination of the listed EBV-immunoassays to confirm an infectious mononucleosis
• Demonstration of IgG antibodies already in the early phase of an EBV infection due to an optimized antigen composition of the EBV VCA IgG immunoassay
• Quantitative determination of all relevant antibody classes for the analysis of paired sera for disease stage monitoring and therapy control
• Detection of intrathecally synthesized EBV VCA and EBNA1 IgG antibodies for CSF diagnostics