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Product Group

ELISA tests for the diagnosis of infectious diseases

Positive control  for immunoassays of the SERION ELISA classic product line.

Control sample pairs for determination of the antibody index

Lyophilized positive control sera for qualitative antibody determination

Control samples for internal quality assurance and guideline compliant practice

Determination of the antibody index (AI) for the detection of intrathecal synthesized antibodies 

Serological detection of antibodies against human pathogens according to the KOLMER technique

SERION software products enable efficient, fast and reliable evaluation of SERION ELISA classic, SERION ELISA antigen and SERION ELISA agile raw data.

Reagent

SERION Avidity Reagents are complementary components which, in combination with the corresponding SERION ELISA classic, enable the avidity determination of pathogen specific IgG antibodies.

For a precise pathogen-specific IgM antibody detection it is necessary to pretreat serum samples with rheumatoid factor RF Absorbent. SERION RF Absorbent precipitates up to 15 mg IgG / ml from undiluted serum.

Pathogen

A variety of bacteria are responsible to some extent for serious infectious diseases. The first diagnosis of a bacterial infection is usually based on clinical symptoms. Commonly, laboratory diagnostics are used to determine the exact pathogen, as the rapid identification of the causative agent is significantly decisive in determining the appropriate therapy.

Viral infections can cause a variety of diseases with a high diversity of clinical symptoms. The pathogen specific diagnosis of a viral disease is carried out by laboratory diagnostics and is supported by serological methods.

Parasitic infections in humans are caused by eukaryotic unicellular Protozoa (including Leishmania and Toxoplasma) and multicellular Metazoa (including tapeworms). Without treatment these infections can lead to clinically manifested damage. The diagnosis is supported by serological methods

Infections with human pathogenic fungi affect, in particular nails, skin and mucous membranes. In at risk patients with reduced immunity these infections often lead to life-threatening invasive mycoses. The most common systemic infections are i.a. caused by Aspergillus fumigatus and Candida albicans.

Diagnostic Category

Children`s diseases or “childhood illness” are usually relatively harmless. However severe complications are also associated to them. The risk of damaging effects can be significantly reduced by a fast pathogen specific diagnosis and timely therapeutic intervention.

The demonstration of antibodies against fungi of the genera Aspergillus and Candida combined with the identification of specific pathogenic antigens is particularly suited to the monitoring of at risk patients. By measuring levels of individual immunoglobulin classes in serial blood samples the early diagnosis of invasive mycoses is enhanced..

Due to their structure, Herpes viruses are amongst the most complex and largest known viruses. These pathogens are responsible for a variety of diseases and are capable of infecting and replicating in a wide range of cell types, such as lymphocytes, nerve cells and epidermal cells. Following infection the viruses remain lifelong in the host organism.

The demonstration of antibody levels against various infectious agents during pregnancy facilitates early disease diagnosis and determination of immunity against pathogens which may be harmful to the unborn child. These pathogens are summarized to the so called “extended TORCH panel”.

Gastrointestinal infections are amongst the most common causes of death globally and can be caused by a wide range of different bacteria or viruses. In particular, the quantification of antibody activities of all relevant immunoglobulin classes allows a comparative study of serum pairs for monitoring disease stage and therapy.

Diseases caused by Chlamydia ssp. affect, in particular, the mucous membranes in the eyes, respiratory tract and genital region and can lead to severe consequences. C. trachomatis infection is one of the most common sexually transmitted bacterial diseases, while C. pneumoniae can cause chronic bronchitis or pneumonia and C. psittaci is the cause of ornithosis (Psittacosis).

Determining the immune status is especially important during pregnancy and for vaccination recommendations. Immune protection often correlates with activity levels of IgG antibodies. The quantitative demonstration of IgG antibody activities is used in particular to confirm and monitor vaccination results and for determination of immune status, e.g. during pregnancy.

Respiratory tract infections, particularly those of bacterial and viral aetiology, are amongst the most common diseases worldwide. The detection of specific antibodies against a variety of pathogens causing respiratory diseases provides a sensitive identification of acute infections as well as supporting the differential diagnosis in cases of atypical pneumonia.

Tropical diseases are infections that occur exclusively or predominantly in tropical or subtropical climate zones. They are mainly the result of infections by parasites or viruses, less frequently bacteria, which are transmitted by blood-feeding insects, primarily mosquitos. As a consequence of climatic changes and increased travel activities, tropical diseases are becoming more significant in temperate latitudes.

Zoonoses are infections caused by the transmission from infected animals to humans. Bacteria, viruses and parasites are frequent causes of such infections. Due to the wide range of symptoms, diagnosis is generally confirmed by laboratory testing in suspected clinical cases.

Product Group
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SERION ELISA control
BC128A
SERION ELISA control
BC128G
SERION ELISA control
BC132A
SERION ELISA control
BC132G
SERION ELISA control
BC132M
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BC120A
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BC120G
SERION ELISA control
BC1201A
SERION ELISA control
BC1201G
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BC121G
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BC121M
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BC116A
SERION ELISA control
BC116G
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BC116M
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BC139A
SERION ELISA control
BC139G
SERION ELISA control
BC139M
SERION ELISA control
BC117A
SERION ELISA control
BC117G
SERION ELISA control
BC117M
SERION ELISA control
BC200
SERION ELISA control
BC148G
SERION ELISA control 
BC148M
SERION ELISA control
BC1371A
SERION ELISA control
BC1371G
SERION ELISA control
BC1371M
SERION ELISA control
BC1372A
SERION ELISA control
BC1372G
SERION ELISA control
BC1372M
SERION ELISA control
BC1312G
SERION ELISA control
BC1312M
SERION ELISA control
BC134A
SERION ELISA control
BC134G
SERION ELISA control
BC134M
SERION ELISA control
BC109G
SERION ELISA control
BC109M
SERION ELISA control 
BC114G
SERION ELISA control
BC114M
SERION ELISA control 
BC1141M
SERION ELISA control
BC130G
SERION ELISA control
BC107G
SERION ELISA control
BC135A
SERION ELISA control
BC135G
SERION ELISA control
BC135M
SERION ELISA control
BC133A
SERION ELISA control
BC133G
SERION ELISA control
BC133M
SERION ELISA control
BC1363G
SERION ELISA control
BC1362G
SERION ELISA control
BC1361G
SERION ELISA control
BC1361M
SERION ELISA control
BC112G
SERION ELISA control
BC112M
SERION ELISA control
BC118A
SERION ELISA control
BC118G
SERION ELISA control
BC118M
SERION ELISA control
BC1051G
SERION ELISA control
BC1051M
SERION ELISA control
BC105A
SERION ELISA control
BC105G
SERION ELISA control
BC105M
SERION ELISA control
BC1052G
SERION ELISA control
BC1052M
SERION ELISA control
BC1231A
SERION ELISA control
BC1231G
SERION ELISA control
BC1231M
SERION ELISA control
BC1232A
SERION ELISA control
BC1232G
SERION ELISA control
BC1232M
SERION ELISA control
BC106G
SERION ELISA control
BC106M
SERION ELISA control 
BC147G
SERION ELISA control
BC125G
SERION ELISA control
BC125M
SERION ELISA control
BC102G
SERION ELISA control
BC102M
SERION ELISA control
BC103G
SERION ELISA control
BC103M
SERION ELISA control
BC127A
SERION ELISA control
BC127G
SERION ELISA control
BC127M
SERION ELISA control
BC126A
SERION ELISA control
BC126G
SERION ELISA control
BC122G
SERION ELISA control
BC122M
SERION ELISA control
BC113A
SERION ELISA control
BC113G
SERION ELISA control
BC129G
SERION ELISA control
BC129M
SERION ELISA control
BC108G
SERION ELISA control
BC110G
SERION ELISA control
BC110M
SERION ELISA control
BC104A
SERION ELISA control
BC104G
SERION ELISA control
BC104M
SERION ELISA control 
BC141G
SERION ELISA control 
BC141G
SERION ELISA control 
BC141M
SERION ELISA control
BC138A
SERION ELISA control
BC138G
SERION ELISA control
BC138M
SERION ELISA control 
BC149A
SERION ELISA control 
BC149G
SERION ELISA control 
BC149M