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Product Group

ELISA tests for the diagnosis of infectious diseases

Positive control  for immunoassays of the SERION ELISA classic product line.

Control sample pairs for determination of the antibody index

Lyophilized positive control sera for qualitative antibody determination

Control samples for internal quality assurance and guideline compliant practice

Determination of the antibody index (AI) for the detection of intrathecal synthesized antibodies 

Serological detection of antibodies against human pathogens according to the KOLMER technique

SERION software products enable efficient, fast and reliable evaluation of SERION ELISA classic, SERION ELISA antigen and SERION ELISA agile raw data.

Reagent

SERION Avidity Reagents are complementary components which, in combination with the corresponding SERION ELISA classic, enable the avidity determination of pathogen specific IgG antibodies.

For a precise pathogen-specific IgM antibody detection it is necessary to pretreat serum samples with rheumatoid factor RF Absorbent. SERION RF Absorbent precipitates up to 15 mg IgG / ml from undiluted serum.

Pathogen

A variety of bacteria are responsible to some extent for serious infectious diseases. The first diagnosis of a bacterial infection is usually based on clinical symptoms. Commonly, laboratory diagnostics are used to determine the exact pathogen, as the rapid identification of the causative agent is significantly decisive in determining the appropriate therapy.

Viral infections can cause a variety of diseases with a high diversity of clinical symptoms. The pathogen specific diagnosis of a viral disease is carried out by laboratory diagnostics and is supported by serological methods.

Parasitic infections in humans are caused by eukaryotic unicellular Protozoa (including Leishmania and Toxoplasma) and multicellular Metazoa (including tapeworms). Without treatment these infections can lead to clinically manifested damage. The diagnosis is supported by serological methods

Infections with human pathogenic fungi affect, in particular nails, skin and mucous membranes. In at risk patients with reduced immunity these infections often lead to life-threatening invasive mycoses. The most common systemic infections are i.a. caused by Aspergillus fumigatus and Candida albicans.

Diagnostic Category

Children`s diseases or “childhood illness” are usually relatively harmless. However severe complications are also associated to them. The risk of damaging effects can be significantly reduced by a fast pathogen specific diagnosis and timely therapeutic intervention.

The demonstration of antibodies against fungi of the genera Aspergillus and Candida combined with the identification of specific pathogenic antigens is particularly suited to the monitoring of at risk patients. By measuring levels of individual immunoglobulin classes in serial blood samples the early diagnosis of invasive mycoses is enhanced..

Due to their structure, Herpes viruses are amongst the most complex and largest known viruses. These pathogens are responsible for a variety of diseases and are capable of infecting and replicating in a wide range of cell types, such as lymphocytes, nerve cells and epidermal cells. Following infection the viruses remain lifelong in the host organism.

The demonstration of antibody levels against various infectious agents during pregnancy facilitates early disease diagnosis and determination of immunity against pathogens which may be harmful to the unborn child. These pathogens are summarized to the so called “extended TORCH panel”.

Gastrointestinal infections are amongst the most common causes of death globally and can be caused by a wide range of different bacteria or viruses. In particular, the quantification of antibody activities of all relevant immunoglobulin classes allows a comparative study of serum pairs for monitoring disease stage and therapy.

Diseases caused by Chlamydia ssp. affect, in particular, the mucous membranes in the eyes, respiratory tract and genital region and can lead to severe consequences. C. trachomatis infection is one of the most common sexually transmitted bacterial diseases, while C. pneumoniae can cause chronic bronchitis or pneumonia and C. psittaci is the cause of ornithosis (Psittacosis).

Determining the immune status is especially important during pregnancy and for vaccination recommendations. Immune protection often correlates with activity levels of IgG antibodies. The quantitative demonstration of IgG antibody activities is used in particular to confirm and monitor vaccination results and for determination of immune status, e.g. during pregnancy.

Respiratory tract infections, particularly those of bacterial and viral aetiology, are amongst the most common diseases worldwide. The detection of specific antibodies against a variety of pathogens causing respiratory diseases provides a sensitive identification of acute infections as well as supporting the differential diagnosis in cases of atypical pneumonia.

Tropical diseases are infections that occur exclusively or predominantly in tropical or subtropical climate zones. They are mainly the result of infections by parasites or viruses, less frequently bacteria, which are transmitted by blood-feeding insects, primarily mosquitos. As a consequence of climatic changes and increased travel activities, tropical diseases are becoming more significant in temperate latitudes.

Zoonoses are infections caused by the transmission from infected animals to humans. Bacteria, viruses and parasites are frequent causes of such infections. Due to the wide range of symptoms, diagnosis is generally confirmed by laboratory testing in suspected clinical cases.

Product Group
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SERION ELISA classic
ESR128A
SERION ELISA classic
ESR128G
SERION ELISA classic
ESR128M
SERION ELISA classic
ESR132A
SERION ELISA classic
ESR132G
SERION ELISA classic
ESR132M
SERION ELISA classic
ESR120A
SERION ELISA classic
ESR120G
SERION ELISA classic
ESR120M
SERION ELISA classic
ESR1201A
SERION ELISA classic
ESR1201G
SERION ELISA classic
ESR121G
SERION ELISA classic
ESR121M
SERION ELISA classic
ESR116A
SERION ELISA classic
ESR116G
SERION ELISA classic
ESR116M
SERION ELISA classic
ESR139A
SERION ELISA classic
ESR139G
SERION ELISA classic
ESR139M
SERION ELISA classic
ESR117A
SERION ELISA classic
ESR117G
SERION ELISA classic
ESR117M
SERION ELISA antigen
ESR200
SERION ELISA classic
ESR148G
SERION ELISA classic
ESR148M
SERION ELISA classic
ESR137A
SERION ELISA classic
ESR137G
SERION ELISA classic
ESR1371A
SERION ELISA classic
ESR1371G
SERION ELISA classic
ESR1371M
SERION ELISA classic
ESR1372A
SERION ELISA classic
ESR1372G
SERION ELISA classic
ESR1372M
SERION ELISA classic
ESR1311A
SERION ELISA classic
ESR1311G
SERION ELISA classic
ESR1312G
SERION ELISA classic
ESR1312M
SERION ELISA classic
ESR134A
SERION ELISA classic
ESR134G
SERION ELISA classic
ESR134M
Avidity Reagent
B109AVID
SERION ELISA classic
ESR109G
SERION ELISA classic
ESR109M
SERION ELISA classic
ESR114G
SERION ELISA classic
ESR114M
SERION ELISA classic
ESR1141M
SERION ELISA classic
ESR130G
SERION ELISA classic
ESR107G
SERION ELISA classic
ESR135A
SERION ELISA classic
ESR135G
SERION ELISA classic
ESR135M
SERION ELISA classic
ESR133A
SERION ELISA classic
ESR133G
SERION ELISA classic
ESR133M
SERION ELISA classic
ESR1363G
SERION ELISA classic
ESR1362G
SERION ELISA classic
ESR1361G
SERION ELISA classic
ESR1361M
SERION ELISA classic
ESR142G
SERION ELISA classic
ESR142M
SERION ELISA classic
ESR112G
SERION ELISA classic
ESR112M
SERION ELISA classic
ESR118A
SERION ELISA classic
ESR118G
SERION ELISA classic
ESR118M
SERION ELISA classic
ESR105A
SERION ELISA classic
ESR105G
SERION ELISA classic
ESR105M
SERION ELISA classic
ESR1051G
SERION ELISA classic
ESR1051M
SERION ELISA classic
ESR1052G
SERION ELISA classic
ESR1052M
SERION ELISA classic
ESR1231A
SERION ELISA classic
ESR1231G
SERION ELISA classic
ESR1231M
SERION ELISA classic
ESR1232A
SERION ELISA classic
ESR1232G
SERION ELISA classic
ESR1232M
SERION ELISA classic
ESR106G
SERION ELISA classic
ESR106M
SERION ELISA classic
ESR147G
SERION ELISA classic
ESR125G
SERION ELISA classic
ESR125M
SERION ELISA classic
ESR102G
SERION ELISA classic
ESR102M
SERION ELISA classic
ESR103G
SERION ELISA classic
ESR103M
SERION ELISA classic
ESR127A
SERION ELISA classic
ESR127G
SERION ELISA classic
ESR127M
SERION ELISA classic
ESR126A
SERION ELISA classic
ESR126G
SERION ELISA classic
ESR122G
SERION ELISA classic
ESR122M
SERION ELISA classic
ESR113A
SERION ELISA classic
ESR113G
SERION ELISA classic
ESR113M
SERION ELISA classic
ESR129G
SERION ELISA classic
ESR129M
Avidity Reagent
B129AVID
SERION RF Absorbent 
Z200
SERION ELISA classic
ESR108G
Avidity Reagent
B110AVID
SERION ELISA classic
ESR110G
SERION ELISA classic
ESR110M
SERION ELISA classic
ESR104A
SERION ELISA classic
ESR104G
SERION ELISA classic
ESR104M
SERION ELISA classic
ESR141G
SERION ELISA classic
ESR141M
SERION ELISA classic
ESR138A
SERION ELISA classic
ESR138G
SERION ELISA classic
ESR138M
SERION ELISA classic 
ESR149A
SERION ELISA classic 
ESR149G